Updated knowledge and a proposed nomenclature for nuclear receptors with two DNA binding domains (2DBD-NRs).
Nuclear receptors (NRs) are important transcriptional modulators in metazoans.Typical NRs possess a conserved DNA binding domain (DBD) and a ligand binding domain (LBD).Since we discovered a type of novel NRs each of them has two DBDs and single LBD (2DBD-NRs) more than decade ago, there has been very few studies Dishwasher Basket Rail Roller about